BBAuthors: Gouda, Weaam; Advisor: -; Participants: Hafiz, Naglaa A.; Mageed, Lamiaa; Alazzouni, Ahmed S.; Khalil, Wagdy K. B.; Afify, Mie; Abdelmaksoud, Mohamed D. E. (2019)
A significant increase of blood glucose was showed in diabetic rats with significant reduction of insulin level compared to non-diabetic controls. The gene expression of insulin and insulin receptor were more significant in diabetic untreated rats compared to the control non-diabetic group. The induction of curcumin as well as Diamicron to diabetic rats normalized significantly their blood sugar level. Also, curcumin-treated rats indicated significant higher in gene expression of insulin and insulin receptor than positive and negative controls.