BBAuthors: Gomaa, Eman Zakaria; Advisor: -; Participants: - (2022)
Halophiles are an excellent source of enzymes that are not only salt stable, but also can withstand and carry out reaction efficiently under extreme conditions. L-glutaminase has attracted much attention with respect to proposed applications in several fields such as pharmaceuticals and food industries. The aim of the present study was to investigate the anticancer activity of L-glutaminase produced by halophilic bacteria. Various halophilic bacterial strains were screened for extracellular L-glutaminase production. An attempt was made to study the optimization, purification, and characterization of L-glutaminase from Bacillus sp. DV2-37. The antitumor activity of the produced enzyme ...