BBAuthors: Enenebeaku, Uchechi E.; Advisor: -; Participants: Ukwandu, Nnamdi C.; Mgbemena, Ifeyinwa C.; Nwigwe, Harriet C.; Enenebeaku, Conrad K.; Duru, Chidi E.; Ogidi, Odangowei I. (2021)
No mortality was recorded in any of the experimental animal groups even at the highest tested dose (5000 mg/kg b.wt) of the extract after monitoring them for 4hrs and subsequently for 7 days. Out of the six extracts, methanolic extracts of the roots and leaves exhibited more antimalarial activity than others. A significant difference (P < 0.05) was statistically observed in the parasite count of groups that received methanol extracts of roots and leaves of D. arborescens. This observation was made when these two extracts were compared with other groups as well as the negative control. However, activity of the standard antimalarial drug (artesunate) was higher (p˂0.05) than those of th...