Protective effects of whey protein mixed with Garcinia kola and olive leaves extract against alloxan-induced oxidative stress and diabetes in rats

Abstract

In comparison with second group, the administration of WP, GK, OL, WP and GK mixture, and WP and OL extracts respectively resulted in significant decrease in blood glucose (61.0 ± 10.8, 68.5 ± 6.6, 64.8 ± 14.6, 82.2 ± 8.4, and 91.7 ± 20 vs. 135.6 mg/dl ± 12.3 respectively). Liver enzymes were improved with administration of WP, GK, and OL extracts compared with positive control. Brain histopathological investigation showed reduction in tissue changes among rats received the suggested interventions.