Biochemical and haematological enhancement activities of aqueous and methanol leaves, stem and roots extracts of Chasmanthera dependens (Hochst) and Dictyandra arborescens (Welw.)

Abstract

Leaves, stem and roots extracts of D. arborescens, as well as extracts of leaves and roots of C. dependens did not record any mice mortality even at 5000 mg/kg b.wt but extracts of C. dependens stem in both medium recorded death at 2900 mg/kg b. wt and 5000 mg/kg b.wt. Ingestion of the extracts by rats over a 14-day period increased (p < 0.05) the body weights of the experimental animals in the C. dependens and D. arborescens treated groups. The relative organ weights of rats that received the extracts did not differ (p < 0.05) significantly from those of the standard and normal control. Administration of the extracts revealed significant (p < 0.05) increase in haematological parameters (PCV, Hb, RBCs, WBCs, MCH, Neutrophils, Lymphocytes and MCHC) at 200 mg/kg−1 body weight. For biochemical parameters, levels of ALT, AST, ALP, total protein, and albumin were not significantly (p < 0.05) elevated following administration of the extracts.