Item Infomation
Title: | Rapidly progressive glomerulonephritis secondary to anti-GBM disease associated with MPO-ANCA: a case report |
Authors: | Isaza-Meza, Mariana |
Participants: | Afanador-Rubio, Diana Carolina Huérfano-Castro, Manuel Alejandro Ramírez-Correa, Ivon Flórez-Vargas, Adriana Alejandra |
Issue Date: | 2023 |
Series/Report no.: | Bulletin of the National Research Centre, Volume 47 (2023), Article number: 42 |
Abstract: | Anti-glomerular basement membrane (GBM) disease, also known as "Goodpasture syndrome," is an autoimmune vasculitis that affects small vessels through the deposit of IgG antibodies against the glomerular and alveolar basal membranes which are visualized as linear deposits in the GBM. The target of these autoantibodies is the non-collagen-1 domain of type IV collagen on the GBM, which presents changes in the structure of the α-345 hexamer, leading to a conformational change that triggers an autoimmune response (Gulati and McAdoo 2018). ANCA-associated vasculitis (AAVs) is a necrotizing vasculitis with few-to-none immune deposits, also affecting small vessels, and is associated with specific antibodies for myeloperoxidase (MPO-ANCA) or proteinase 3 (PR3-ANCA) |
URI: | http://tailieuso.tlu.edu.vn/handle/DHTL/12913 |
Source: | https://link.springer.com/article/10.1186/s42269-023-01020-1 |
ISSN: | 2522-8307 |
Appears in Collections: | Tài liệu mở |
ABSTRACTS VIEWS
45
VIEWS & DOWNLOAD
0
Files in This Item:
There are no files associated with this item.
Bạn đọc là cán bộ, giáo viên, sinh viên của Trường Đại học Thuỷ Lợi cần đăng nhập để Xem trực tuyến/Tải về
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.