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  • Authors: Sharma, Arun Dev;  Advisor: -;  Participants: Kaur, Inderjeet (2022)

  • Aspergillosis, has recently confounded some states of India. Due to major role in fungal cell wall synthesis, in the present study UDP-glycosyltransferase, Glucosamine-6-phosphate synthase and chitin synthase were chosen as an appropriate sites to design drug. The objective of present study was molecular docking of lemon grass essential oil component citral and in vitro validation. GC-FID analysis was used to find out aromatic profile. For docking, Patch-dock analysis was used. Ligand Protein 2D and 3D Interactions were also studied. Drug likeliness, and toxicity profile were also studied. Docking analysis indicated effective binding of citral to UDP-glycosyltransferase, Glucosamine-6-phosphate synthase and chitin synthase. In vitro validation was performed by fungal strain Aspergil...

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  • Authors: Noor, Rashed;  Advisor: -;  Participants: Shareen, Saadia; Billah, Muntasir (2022)

  • The world has been suffering from the COVID-19 pandemic (officially declared by WHO in March 2020), caused by the severe acute respiratory β-coronavirus 2 (SARS-CoV-2) since the last week of December 2019. The disease was initially designated as a Public Health Emergency of International Concern on January 30, 2020. In order to protect the health of mass public, an array of research on drugs and vaccines against SARS-CoV-2 has been conducted globally. However, the emerging variants of SARS-CoV-2, i.e., Alpha (B.1.1.7), Beta (B.1.351), Gamma (P.1), and Delta (B.1.617.2) variants which evolved in late 2020 and the Omicron variant (B.1.1.529) which emerged in November 2021 along with its subvariant BA.2 which was first identified in India and South Africa in late December 2021, have ra...

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  • Authors: Muche, Meseret;  Advisor: -;  Participants: Yemata, Getahun; Molla, Eyayu; Muasya, A. Muthama; Tsegay, Berhanu Abraha (2022)

  • The Coronavirus (COVID-19) is a global pandemic caused by SARS-CoV-2, which has an enormous effect on human lives and the global environment. This review aimed to assess the global scientific evidence on the impact of COVID-19 lockdown on natural resources using international databases and search engines. Thus, the unprecedented anthropause due to COVID-19 has positive and negative effects on natural resources.

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  • Authors: Choudhury, Priyanka Ray;  Advisor: -;  Participants: Saha, Tapoja; Goel, Sachin; Shah, Janvi Manish; Ganjewala, Deepak (2022)

  • The majority of pandemics are known to be a result of either bacteria or viruses out of which viruses seem to be an entity of growing concern due to the sheer number of yet unidentified and potentially threatening viruses, their ability to quickly evolve and transform, their ability to transfer and change from one host organism to another and the difficulty in creating safe vaccines on time.

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  • Authors: Lounis, Mohamed;  Advisor: -;  Participants: Bagal, Dilip Kumar (2020)

  • Results showed that the peak of the epidemic will be reached on September 8th, 2021 and the total infected persons will exceed 800,000 cases at the end of the epidemic. Also, more than 15 million persons will be susceptible. The reproduction number (R0) is estimated at 1.23254.

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  • Authors: Aidoo, Eric N.;  Advisor: -;  Participants: Adebanji, Atinuke O.; Awashie, Gaston E.; Appiah, Simon K. (2021)

  • Results obtained showed that wind speed and atmospheric pressure have positive linear relationship with the spread of infection an increase in the risk of COVID-19 spread. In addition, the risk of spread fluctuates for temperature between 24 and 29 °C but sharply decreases when average temperature exceeds 29 °C. The risk of spread of COVID-19 significantly decrease for relative humidity between 72 and 76% and leveled afterwards.

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  • Authors: Fouad, Ghadha Ibrahim;  Advisor: -;  Participants: - (2021)

  • The neuroinvasive potential of SARS-CoV-2 might contribute to its fatal behavior. Understanding the underlying mechanisms of this novel neuropathogen might contribute to the development of effective therapeutic strategies. The manifestations of neural damage in COVID-19 patients ranged from headache to severe encephalopathy and progression of preexisting neural disorders, it is speculated that neuroinvasion is strongly linked to the fatal respiratory dysfunction. The underlying neuropathological impact of emerging pneumonia (COVID-19) is still unclear.

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  • Authors: Nabih, Heba K.;  Advisor: -;  Participants: - (2021)

  • The global coronavirus disease 2019 (COVID-19) was announced as pandemic by the World Health Organization (WHO). With the increased number of infected and dead victims daily all over the world, it becomes necessary to stop or overcome its rapid spread. Although the production of vaccine or even specified effective anti-virus may take about six months to a year, intravenous immunoglobulin (IVIg) may be clinically used as a safe treatment to save and improve the quality of life of patients with a variety of immunodeficiency diseases such as lymphocytopenia, which is a common clinical feature in COVID-19. Through the current review, it was concluded that this passive immunization may promote the immunity to better fight against the virus, so the survival of the patients could be kept l...