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Authors: Malave, Brian; Advisor: -; Participants: - (2023) - Selective androgen receptor modulators (SARMs) are becoming increasingly common amongst athletes and the general population, but their side effect profile in human subjects at recreational doses is understudied.
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Authors: Ayeni, Temitope Oluwatosin; Advisor: -; Participants: Arotupin, Daniel Juwon; Ayo, Oisagah Ezekiel (2022) - Table 1 shows counts from three different dilutions (10−5, 10−6 and 10−7). Fungal colonies decrease with increasing dilution. The number of fungal colonies is least in 10−7 and highest in 10−5 for all plates. Hence, the number of fungal colonies decreases with increasing concentration.
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Authors: Abdullahi, Mustapha; Advisor: -; Participants: Adeniji, Shola Elijah; Arthur, David Ebuka; Musa, Shuaibu (2020) - At first, the structure of the compounds was accurately drawn and optimized using the Spartan 14 software at DFT level of theory with B3LYP/6-31G** basis set in a vacuum. The diverse chemometric descriptors were computed from the optimized structures using the PaDEL descriptors software, and the division of the dataset into training and test sets was done based on Kennard-Stone’s algorithm. Five (5) models were generated from the training set using genetic function approximation, and model 1 was chosen as the best due to its robust internal and external validation metrics (R2train = 0.8563, R2adjusted = 0.8185, PRESS = 3.5724, average R¯¯¯¯2m (LOO-train) = 0.6751, Q2cv = 0.7534, R2pred= 0.7543, R2test = 0.6993) which passed the model criteria of acceptability. 6-Bromo-N-(2-(4-bromop...
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Authors: Radwan, M. M.; Advisor: -; Participants: Nagi, Shaymaa M. (2022) - Evaluation of the final setting time was carried out on the material pastes of normal consistency prepared with distilled water at a liquid/solid ratio of 0.23 ml/g as given in “Setting time” section. The recorded average setting time was 20 min at 37 °C (average of five readings). Figure 3 shows the hardness data of samples cured in the different hydration media at all curing ages. Figure 3 indicates that the hardness values of samples cured in distilled water (DW) increase with the hydration period from one day and up to 14 days, while for samples cured in SBF solution and the Pseudomonas aeruginosa microbe in MHB media there was a decrease in the hardness values at all curing ages. However, the samples immersed in the microbe medium showed slightly higher hardness values than tho...
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Authors: Gharge, Shankar; Advisor: -; Participants: Koli, Rahul; Gudasi, Sachin; I. Hiremath, Sushmita (2023) - Heart Study has been operating for more than 40 years, and throughout that time it has found a number of risk variables that interact negatively to have an overall negative effect on cardiovascular disease (CVD) with an estimated 17.9 million deaths per year, CVD is the world's leading cause of death.
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Authors: Matee, Mecky; Advisor: -; Participants: Mshana, Stephen E.; Mtebe, Majigo; Komba, Erick Vitus; Moremi, Nyambura; Lutamwa, Julius; Kapona, Otrida; Sekamatte, Musa; Mboera, Leonard E. G. (2023) - Antimicrobial resistance is a global problem and involve pathogens which have the potential to move between food producing animals and humans by direct exposure or through the food chain or the environment. The objective of this study was to determine the performance in addressing antimicrobial resistance in Kenya, Tanzania, Uganda and Zambia. Desk review and in-depth interviews were employed for data collection. Interviews were conducted with national antimicrobial resistance focal officials.
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Authors: Muser, Olga; Advisor: -; Participants: Seiler, Kevin; Bachnick, Stefanie; Gehri, Beatrice; Zúñiga, Franziska; Hasemann, Wolfgang (2022) - During the study period, 211 patients were hospitalized on the six wards, of whom 116 were included in the study. A total of 95 patients were excluded due to, for instance, refusal to participate (n = 29), admission after assessment (n = 22) or absence of patients (n = 19) (Fig. 2).The median age of patients was 73.0 years (interquartile Q1 56.3, Q3 83.0) and 49 (42.2%) of the patients were women. Pre-existing dementia was present in 11 (9.5%) patients. A total of 8 out of 116 patients (6.9%) had delirium according to the gold standard, the mCAM-ED, and 16 (13.8%) had delirium according to the 4AT. Subgroup analysis of patients with delirium and patients without delirium showed no statistically significant difference in the development of delirium in respect to age (U = −1.799, p = ...
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Authors: Bhuiyan, Asma Akter; Advisor: -; Participants: Brahmachari, Sreyashi; Ripa, Israt Jahan; Noor, Rashed (2022) - At the end of December 2019, numerous people with pneumonia symptoms were admitted to the hospitals of Wuhan, Hubei region of China, and within a short period of time, it spread globally and became a pandemic (Liu et al. 2020). First, “Wuhan pneumonia” was coined to indicate the symptoms; soon after, it was discovered that the causative agent of the disease was “Coronavirus” which belongs to the “Coronaviridae” family and β coronavirus genus (Pal et al. 2020; Noor 2021; Noor and Maniha 2020). Subsequently, the name severe acute respiratory coronavirus 2 (SARS-CoV-2) took place (Pal et al. 2020). The World Health Organization (WHO) entitled this pandemic as “COVID-19” disease on March 11 2020, which consists of a genome sequence with an elevated degree of similarity with the earliest...
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Authors: Borodo, Safiya Bala; Advisor: -; Participants: Jatau, Abubakar Ibrahim; Mohammed, Mustapha; Aminu, Nafiu; Shitu, Zayyanu; Sha’aban, Abubakar (2022) - The burden of polypharmacy and PIMs in Nigeria
In Nigeria, polypharmacy is common in clinical practice settings. Patients using between six and twelve medications have a higher risk of adverse drug events than patients with a lower quartile of drug use (Steinman et al. 2006). Akande and Ologe found that polypharmacy (particularly involving injectable formulations) and under-usage of life-saving drugs were common at a secondary healthcare facility in the North-central region of the country (Akande and Ologe 2007). The major risk factors for polypharmacy were reported as age, level of education, and diagnosis (Igbinomwanhia et al. 2017). The burden of polypharmacy had several clinical effects on the patients, ranging from medication non-compliance, addiction to drug interactions
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Authors: Pawal, Pratibha; Advisor: -; Participants: Aute, Tukaram (2023) - Primary hypertriglyceridemia (HTG) is a very rare autosomal recessive disorder caused by the mutations of the genes related with triglyceride metabolism, including apolipoproteins and lipoprotein lipase (LPL) among others. Germline mutations in the LPL gene cause familial LPL deficiency with an incidence of about 1:1,000,000. It is often diagnosed in childhood and consanguinity is common.
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