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  • Acute disseminated encephalomyelitis following the COVID-19 vaccine Ad26.COV2.S, a case report

    • Authors: Gustavsen, Stefan;  Advisor: -;  Participants: Nordling, Mette Maria; Weglewski, Arkadiusz (2023)

  • The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic has been leading to dramatic health, social and economic problems around the world. It was necessary to introduce worldwide vaccination program against SARS-CoV-2 virus. Vaccination of billions of people around the world leads to many questions about risk of vaccines and possible side effects. It is well known that acute disseminated encephalomyelitis (ADEM) is a rare, but possible complication of vaccines. Previously, cases of ADEM following various COVID-19 vaccines, including the vaccines from AstraZenica, Pfizer, Sputnik V, SinoVac, Moderna, Sinopharm, have been described. In this case report, we present the first documented case of ADEM following the COVID-19 vaccine Ad26.COV2.S from Johnson & Johnson.
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  • The long-term impact of coronavirus disease 2019 on environmental health: a review study of the bi-directional effect

    • Authors: Chakraborty, Prasenjit;  Advisor: -;  Participants: Kumar, Randhir; Karn, Sanjay; Srivastava, Ankit Kumar; Mondal, Priya (2023)

  • In early December 2019, an unusual pneumonia outbreak in Wuhan city, China, created an unprecedented and irreversible impact on the entire world 2/24/2023 12:58:00 PM. The symptoms of COVID-19 range from mild to severe, and include mainly fever, cough, and respiratory distress. Severe cases of pneumonia and hypoxemia result in considerable mortality (Rothan and Byrareddy 2020). The etiology has been linked to the new strain of coronavirus (SARS-CoV-2). According to the COVID-19 weekly epidemiological update by the World Health Organization (WHO), as of 9 May 2021, there have been a total of 163,965,336 COVID-19 cases with 3,397,147 fatalities (World Health Organization 2021). However, the new dynamics of the outbreaks seem highly variable among countries
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  • Identification of consensus hairpin loop structure among the negative sense subgenomic RNAs of SARS-CoV-2

    • Authors: Bokolia, Naveen Prakash;  Advisor: -;  Participants: Gadepalli, Ravisekhar (2023)

  • Previous research investigation determined the abundance levels of subgenomic RNAs from the COVID-19 patient samples (Alexandersen et al. 2020). Authors mapped the NGS reads data to subgenomic RNAs in order to identify the abundance of particular subgenomic RNA from the patient samples (Alexandersen et al. 2020). NGS reads mapped results revealed that Orf7a and N subgenomic were in high abundance, whereas Orf8, Orf6, and E subgenomic were relatively low (in an increasing order). These subgenomic RNAs are present several fold higher in comparison with whole genome fragments. Therefore, the present study seek to identify the possible conserved regions nearby the TRS or initiation codon which could mediate significant roles in the generation or expression of subgenomic RNAs.
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