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  • An overview on COVID-19: reality and expectation

    • Authors: Hamed, Manal A.;  Advisor: -;  Participants: - (2020)

  • Under this emergency situation that the world facing against COVID-19, there are about 15 potential vaccine candidates tested globally based on messenger RNA, DNA-based, nanoparticle, synthetic, and modified virus-like particle. Certain drugs that are clinically approved for other diseases were tested against COVID-19 as chloroquine, hydroxychloroquine, ivermectin, favipiravir, ribavirin, and remdesivir. Convalescent plasma transfusion and traditional herbal medicine were also taken into consideration. Due to the absence of effective treatment or vaccines against COVID-19 so far, the precautionary measures according to WHO’s strategic objectives are the only way to confront this crisis. Governments should adopt national medical care programs to reduce the risk of exposure to any fut...
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  • Molecular targets and system biology approaches for drug repurposing against SARS-CoV-2

    • Authors: Singh, Rahul Kunwar;  Advisor: -;  Participants: Yadav, Brijesh Singh; Mohapatra, Tribhuvan Mohan (2020)

  • COVID-19, a pandemic declared by WHO, has infected about 39.5 million and killed about 1.1 million people throughout the world. There is the urgent need of more studies to identify the novel drug targets and the drug candidates against it to handle the situation.
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  • How successful Bangladesh is in controlling the coronavirus pandemic?

    • Authors: Akanda, Ayatullah Al Musabi;  Advisor: -;  Participants: Ahmed, Redwan (2020)

  • The results show that simulated number of patients (without policy measures) surpassed the actual number of patients (with policy measures) from the first week of July 2020 which may provide a signal about the positive impact of policy measures taken by the government.
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  • Serial computed tomography findings of Coronavirus disease 2019 (COVID-19) pneumonia treated with favipiravir and steroid therapy: report of 11 cases

    • Authors: Irizato, Naoki;  Advisor: -;  Participants: Hiroshi Matsuura, &; Okada, Atsuya; Ueda, Ken; Yamamura, Hitoshi (2021)

  • Eleven patients with severe COVID-19 pneumonia were included. CT findings assessed at the three time points showed that all patients had ground-glass opacities (GGO) and consolidation and mixed pattern at intubation. Consolidation and mixed pattern disappeared in most of the patients whereas GGO persisted in all patients at 1-month follow-up. In addition to GGO, a subpleural line and bronchus distortion and bronchial dilatation were frequent findings. The degree of resolution of GGO varied depending on each patient. The GGO score correlated significantly with the time from symptoms onset to initiation of steroid therapy (ρ = 0.707, p = 0.015).
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  • Evaluating the impact of COVID-19 pandemic lockdown on education in Nigeria: Insights from teachers and students on virtual/online learning

    • Authors: Ebohon, Osamudiamen;  Advisor: -;  Participants: Obienu, Anayochukwu Chukwunonso; Irabor, Francis; Amadin, Frank Iwebuke; Omoregie, Ehimwenma Sheena (2021)

  • A total of 703 students and 60 teachers from five different local universities participated in this study. All participants (> 50%) had difficulties with Internet connection. Students (67%) as well as teachers (59%) agree that they had limited interactions with one another and this negatively influence student’s satisfaction (p < 0.01). While students were split on the most appropriate method of assessment, teachers (63%) believe assignments and oral examinations are more suitable for online teaching. Many teachers (66%) admitted that it was difficult assessing students’ abilities and performance. Some students (> 40%) were concerned about the number of assignments given. Most teachers (84%) believe there is an increase in tendency for examination malpractice when assessment was con...
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  • The COVID-19 basic reproductive ratio using SEIR model for the Middle East countries and some other countries for two stages of the disease

    • Authors: Al-Raeei, Marwan;  Advisor: -;  Participants: - (2021)

  • We employ Runge–Kutta method on SEIR model to simulate the basic reproductive ratio values of SARS-CoV-2 disease by using the recorded data of the disease for two stages, up to date May 29, 2020, in the first stage and up to date September 7, 2020, in the second stage. We estimate the coefficient of exposing rate, the coefficient of infection rate, the coefficient of recovery rate and the coefficient of mortality rate of the new coronavirus disease in addition to the basic reproductive ratio values of the disease in the Middle East countries, namely Bahrain, Cyprus, Egypt, Iran, Iraq, Jordan, Kuwait, Lebanon, Oman, Qatar, Saudi Arabia, the Syrian Arab Republic, the United Arab Emirates, Turkey and Yemen where we apply the SEIR epidemic model.
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  • COVID-19 vaccine hesitancy: a systematic review of barriers to the uptake of COVID-19 vaccine among adults in Nigeria

    • Authors: Babatope, Tolulope;  Advisor: -;  Participants: Ilyenkova, Vera; Marais, Debbi (2023)

  • A total of 161 records identified from the four databases were exported into Rayyan systematic review software and duplicates were removed, leaving 148 records to be screened (Fig. 2). The kappa test of inter-rater agreement between reviewers was 0.83. Full-text screening was conducted to further assess the remaining 23 articles for eligibility before data extraction. Eight articles were excluded mainly due to being the wrong publication type (n = 4) or having the wrong outcome (n = 4). At the end of the process, 15 articles were eligible for inclusion in the review with an inter-rater agreement of κ = 0.95.
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  • An outline of SARS-CoV-2 pathogenesis and the complement cascade of immune system

    • Authors: Hembram, Padmalochan;  Advisor: -;  Participants: - (2021)

  • Coronavirus disease 19 is a viral infection caused by a novel coronavirus, SARS-CoV-2. It was first notified in Wuhan, China, is now spread into numerous part of the world. Thus, the world needs urgent support and encouragement to develop a vaccine or antiviral treatments to combat the atrocious outbreak.
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  • Regression tree modelling to predict total average extra costs in household spending during COVID-19 pandemic

    • Authors: Lotfy, Nesma;  Advisor: -;  Participants: - (2021)

  • Most of the respondents were females (81%) and aged between 30 and 40 (56.3%). About 63.1% of families had the same monthly income while 35.4% had a decrease in monthly income. A significant reduction in days of leaving home before and after COVID-19 pandemic was observed (before; median = 6, after; median = 5, P =  < 0.001). The extra spending in grocery was the dominated item compared to other items (mean = 707.2 L.E./month, SD = 530.7). Regarding regression tree, the maximum average extra costs due to COVID-19 pandemic were 1386 L.E./month (around 88.56$/month (1$—> 15.65L.E.)) while the minimum average extra costs were 217 L.E./month (around 13.86$/month).