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Tác giả: Muhammad, Yasin Ali; Người hướng dẫn: -; Người tham gia: - (2022) - At the time of this writing, SARS-CoV-2 has reportedly claimed the lives of millions of people worldwide. However, there is still disagreement concerning the origin of SARS-CoV-2, its true nature, and the extent of its pathogenicity. Thus, the purpose of this manuscript is to highlight and critically analyze these differences so that research efforts can be geared toward addressing these concerns.
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Tác giả: Choudhury, Priyanka Ray; Người hướng dẫn: -; Người tham gia: Saha, Tapoja; Goel, Sachin; Shah, Janvi Manish; Ganjewala, Deepak (2022) - The majority of pandemics are known to be a result of either bacteria or viruses out of which viruses seem to be an entity of growing concern due to the sheer number of yet unidentified and potentially threatening viruses, their ability to quickly evolve and transform, their ability to transfer and change from one host organism to another and the difficulty in creating safe vaccines on time.
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Tác giả: Muche, Meseret; Người hướng dẫn: -; Người tham gia: Yemata, Getahun; Molla, Eyayu; Muasya, A. Muthama; Tsegay, Berhanu Abraha (2022) - The Coronavirus (COVID-19) is a global pandemic caused by SARS-CoV-2, which has an enormous effect on human lives and the global environment. This review aimed to assess the global scientific evidence on the impact of COVID-19 lockdown on natural resources using international databases and search engines. Thus, the unprecedented anthropause due to COVID-19 has positive and negative effects on natural resources.
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Tác giả: Rahul Gupta; Người hướng dẫn: -; Người tham gia: - (2022) - The hyperinflammatory state leading to an aberrant cytokine production, culminating in acute respiratory distress syndrome, sepsis and multi-organ dysfunction contribute much to the pathophysiologies of severe COVID-19. These severe patients have similar clinical manifestations with patients suffering from certain auto-inflammatory disorders and cytokine storm syndromes. Interestingly, anakinra (blocking both IL-1α and IL-1β) has shown promises in treating these patients with hyperinflammatory disorders, sepsis with multiorgan failures. Another inflammasome, AIM2, involved in production of IL-1 has also been found to be implicated in COVID-19. IL-1β, a known procoagulant, causes induction of tissue factor with increasing vascular endothelial permeability loss ensuing in hypercoagula...
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Tác giả: Giri, Simran; Người hướng dẫn: -; Người tham gia: Sen, Sanjukta; Singh, Rohan; Paul, Paramita; Sahu, Ranabir; Nandi, Gouranga; Dua, Tarun Kumar (2022) - The World Health Organization declared the outbreak of the novel coronavirus (COVID-19) as a global health emergency on January 30, 2020, and as a pandemic disease on March 11, 2020. This review highlights the international situation, risk factors, and related protections to be taken as prerequisite measures and probable treatment options for the COVID-19-infected population in the current scenario.
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Tác giả: Suri, Arpita; Người hướng dẫn: -; Người tham gia: Singh, Naveen Kumar; Perumal, Vanamail (2022) - COVID-19 outbreak has engulfed different parts of the world, affecting more than 163 million people and causing more than 3 million deaths worldwide due to human transmission. Thus, it has become critical to identify the risk factors and laboratory parameters to identify patients who have high chances of worsening clinical symptoms or poor clinical outcomes. Therefore, the study aims to identify inflammatory markers that can help identify patients at increased risk for progression to critical illness, thus decreasing the risk of any mortality. Our study focussed on the predictive utility of C-reactive protein, Interleukin-6, D-dimer and Procalcitonin in assisting the management of COVID-19 patients with adverse clinical effects. Through literature search in electronic databases, we ...
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Tác giả: Kabir, Humayun; Người hướng dẫn: -; Người tham gia: Hasan, Md. Kamrul; Rahman, Mamunur; Akter, Shimpi; Chowdhury, Golam Ishraque; Bhuya, Mohammad Toyabur Rahaman; Mitra, Dipak Kumar (2022) - Mucormycosis, a severe fungal infection, is an emerging public health concern during the COVID-19 pandemic. This study aimed to investigate the perception of mucormycosis among Bangladeshi healthcare workers.
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Tác giả: Sharma, Arun Dev; Người hướng dẫn: -; Người tham gia: Kaur, Inderjeet (2022) - Aspergillosis, has recently confounded some states of India. Due to major role in fungal cell wall synthesis, in the present study UDP-glycosyltransferase, Glucosamine-6-phosphate synthase and chitin synthase were chosen as an appropriate sites to design drug. The objective of present study was molecular docking of lemon grass essential oil component citral and in vitro validation. GC-FID analysis was used to find out aromatic profile. For docking, Patch-dock analysis was used. Ligand Protein 2D and 3D Interactions were also studied. Drug likeliness, and toxicity profile were also studied. Docking analysis indicated effective binding of citral to UDP-glycosyltransferase, Glucosamine-6-phosphate synthase and chitin synthase. In vitro validation was performed by fungal strain Aspergil...
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Tác giả: Singla, Shivali; Người hướng dẫn: -; Người tham gia: Goyal, Sachin (2022) - The study was aimed at encapsulating the evidence of in vitro and in vivo antiviral activities of molnupiravir and its active form against highly pathogenic SARS-CoV-2, the pathogen responsible for COVID-19, and finding out the efficacy and safety of molnupiravir in clinical trials.
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Tác giả: Sami, Saad Ahmed; Người hướng dẫn: -; Người tham gia: Ahmed, Saad (2022) - The terms ‘lockdown’, ‘quarantine’ and ‘isolation’ were alien to most people of Bangladesh before the emergence of COVID-19 infection. Geographically, being closed to disease epicenter China, Bangladesh also fall victim to this deadly virus and still undergoing critical conditions. This catastrophic situation has negatively impacted physical and mental health; disrupted economy, education, social aspects.
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