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  • Authors: Zhang, S.;  Advisor: -;  Participants: Bamakan, S. M. H.; Qu, Q.; Li, S. (2019)

  • With the recent advancements in analyzing high-volume, complex, and unstructured data, modern learning methods are playing an increasingly critical role in the field of personalized medicine. Personalized medicine (i.e., providing tailored medical treatment to individual patients through the identification of common features, including their genetics, inheritance, and lifestyle) has attracted the attention of many researchers in recent years. This paper provides an overview of the research progress in the application of learning methods, with a focus on deep learning in personalized medicine. In particular, three domains of applications are reviewed: drug development, disease characteristic identification, and therapeutic effect prediction. The main objective of this review is to cons...

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  • Authors: Tao, R.;  Advisor: -;  Participants: Zhang, S.; Huang, X.; Tao, M.; Ma, J.; Ma, S.; Zhang, C.; Zhang, T.; Tang, F.; Lu, J.; Shen, C.; Xie, X. (2019)

  • Objective: This study focused on developing a fast and accurate automatic ischemic heart disease detection/localization methodology. Methods: Twavewas segmented from averaged Magnetocardiography (MCG) recordings and 164 features were subsequently extracted. These features were categorized into three groups: time domain features, frequency domain features, and informa-tion theory features. Next, we compared different machine learning classifiers including: k-nearest neighbor, decision tree, support vector machine (SVM), and XGBoost. To identify ischemia heart disease (IHD) case, we selected three classifiers with best performance and applied model ensemble to average results. All 164 features were used in this stage. To localize ischemia, we classified IHD group according to stenosis ...

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