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Authors: Elsayed, Shaimaa I. M.; Advisor: -; Participants: Glala, A. A.; Abdalla, Aboelfetoh M.; El-Sayed, Abd El Ghafour A.; Darwish, Mona A. (2020) - The results demonstrated that dill cv. Dukat gave the highest plants (cm), maximum leaf number per plant, pigment content (mg/g), total carbohydrates (%), nitrogen, and phosphorus percentages in the vegetative growth stage. Meanwhile, dill cv. Balady recorded the maximum potassium percentage and low content of nitrate accumulation (mg/kg) in the vegetative growth stage. Both dill cultivars contained antioxidants without significant differences between them. The best fertilization treatments were 100% organic fertilization with biofertilizer and 100% chemical fertilizer for plant height (cm), leaf number per plant, pigment content, antioxidant percentage, total carbohydrate percentage, and N and P percentages of two dill genotypes. On the other hand, 50% organic fertilization with bi...
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Authors: Alisi, Ikechukwu Ogadimma; Advisor: -; Participants: Uzairu, Adamu; Abechi, Stephen Eyije (2020) - The investigated compounds were able to scavenge HOO· and CH3OO· radicals by HAT and SPLET mechanisms in the gas phase and aqueous solution, based on the computed results of reaction enthalpies and Gibbs free energy. The SET-PT mechanism for these compounds was observed to be thermodynamically unfeasible in the gas phase. However, the thermodynamic feasibility of free radical scavenge by SET-PT mechanism was observed in aqueous solution. Among the investigated compounds, MCC 009 (1E,4E)-1-(3-(aminomethyl)-4-hydroxyphenyl)-5-(4-hydroxy-3-((hydroxy (methyl)amino) methyl)phenyl) penta-1,4-dien-3-one at the 19-OH position possessed the highest capacity to scavenge both HOO· and CH3OO· radicals by HAT, SET-PT, and SPLET mechanisms.
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Authors: Hussein, Ahmed M.; Advisor: -; Participants: Yaseen, Attia A.; Esmail, Ramadan M.; Mohammad, Ayman A. (2020) - The antioxidant activity of the PC extract of FM is considerably high when measuring it by the three methods (the β-carotene coupled oxidation method, the DPPH free radical scavenging activity method, and measuring the reducing antioxidant power). The toxicity test revealed that the PC extract was nontoxic on normal retina cell line. Also, it has no anticoagulating activity. Evaluation of antimicrobial activity showed that it is effective towards four strains only from seven. FM phenolic extract has been evaluated as chemo-preventive agents by testing the product for any cytotoxic activity against human tumor cell lines. The highest inhibitory effect was achieved on cell lines of colon carcinoma and lung carcinoma with IC50 = 22.3 and 22.6 μ/ml respectively.
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Authors: Kora, Aruna Jyothi; Advisor: -; Participants: - (2020) - Se-enriched mushrooms are produced by cultivation on substrates enriched with either inorganic or organic forms of Se and Se-hyperaccumulated agricultural residues. Edible mushrooms accumulate Se from substrate into selenoproteins and selenoenzymes as selenomethionine and selenocysteine, the organic and most bioavailable forms of Se. Without affecting the biological efficiency, the enrichment process enhances the total protein and total phenolic content and bioaccessibility of trace elements. The antioxidant action was higher for Se-fortified mushrooms in terms of total phenolics, total antioxidant, 1, 1-diphenyl-dipicrylhydrazyl (DPPH) scavenging, metal chelating, and lipid peroxidation inhibition activities in comparison with unfortified mushrooms. Also, Se-enriched mushrooms are ...
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Authors: Oyeyemi, Wahab Adekunle; Advisor: -; Participants: Akinola, Adeniran Oluwadamilare; Daramola, Oore-oluwapo Ololade; Aikpitanyi, Ikponmwosa; Durotoluwa, Opeyemi Tosin; Alele, Precious-Gift Olohigbe; Ogieriakhi, Iyesogie Osaretin; Okoro, Tseye Daisy (2022) - Heavy metals are well documented to induce reproductive toxicity. This study was designed to investigate the role of vitamin E and quercetin on reproductive toxicity mediated by lead acetate in male Wistar rats. Thirty male adult Wistar rats were grouped into six (n = 5 per group) as follows: Group 1 (Control); Group 2 and 3 were administered with 100 mg/kg vitamin E and quercetin, respectively; Group 4 was administered with 30 mg/kg lead acetate; Groups 5 and 6 received lead acetate with vitamin E and lead acetate with quercetin, respectively.
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Authors: Goldar, Waquar Ahmed; Advisor: -; Participants: Jana, Sandipan; Kumari, Reshma; Bhattacharya, Sanjib; Haldar, Pallab Kanti (2022) - Litsea cubeba (Lour) Pers. (Lauraceae) fruit has traditionally been used in treatment of diabetes in Sikkim, India. The purpose of the present study is to investigate the antidiabetic activity of methanol extract of Litsea cubeba fruit (MELCF) against streptozotocin (STZ)-induced diabetes in male albino mice. MELCF was assessed for in vitro α amylase, α glucosidase inhibitory activity and in vitro antioxidant activity against 2-diphenyl-1-picrylhydrazyl (DPPH) and nitric oxide radicals. STZ was given intraperitoneally at 60 mg/kg for consecutive 3 days to mice. MELCF was administered orally in three doses 100 mg/kg, 200 mg/kg, 300 mg/kg body weight to STZ-induced mice. Metformin (200 mg/kg body weight) served as reference. Blood glucose and body weight were checked in seven days int...
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Authors: Adeyemo, Aanuoluwapo Elizabeth; Advisor: -; Participants: Omoba, Olufunmilayo Sade; Olagunju, Aderonke Ibidunni; Josiah, Sunday Solomon (2022) - Plant foods have gained tremendous consideration as a significant progenitor of bioactive substances with several therapeutic advantages over synthetic drugs. Shallot (Allium ascalonicum L.) together with plantain (Musa paradisiaca L.; particularly unripe ones) holds their applications as spice/food and folk medicine. Hence, this research pursues to explore the chemical composition, antioxidant activities (in vitro), and phenolic profile of shallot-enriched plantain biscuits. Processed shallot flour and unripe plantain flour were blended in different proportions (100% Plantain (SB0), 95% Plantain + 5% Shallot (SB5), 90% Plantain + 10% Shallot (SB10), 85% Plantain + 15% Shallot biscuit (SB15) and 80% Plantain + 20% Shallot biscuit (SB20), mixed with other ingredients to prepare biscu...
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Authors: Fapetu, Aanuoluwapo Patricia; Advisor: -; Participants: Karigidi, Kayode Olayele; Akintimehin, Emmanuel Sina; Olawuwo, Tomilayo; Adetuyi, Foluso Olutope (2022) - Moringa oleifera leaf is a prominent leaf in folk medicine used to treat many diseases including diabetes mellitus. This study is aimed at determining the effects of substitution of wheat flour with Moringa oleifera leaf powder (MOLP) on physical, nutritional, bioactive, antioxidant and antidiabetic properties of cookies. Wheat flour was substituted with MOLP (2.5%, 5% and 10%) in the baking of the cookies (C1, C2 and C3, respectively), and its effects were evaluated on proximate, bioactive compounds, antioxidant, physical and inhibitory properties against α-amylase and α-glucosidase enzymes using standard methods. Also, sensory attributes of the cookies were determined using 9-point hedonic point.
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Authors: Awolu, Olugbenga O.; Advisor: -; Participants: Fole, Esosa T.; Oladeji, Oluwatoyin A.; Ayo-Omogie, Helen N.; Olagunju, Aderonke I. (2022) - This study evaluated the antioxidant activities of avocado seed extract as affected by solvent for extraction and formulation of microcapsule from the extract. Avocado seed powder was extracted using ethanol, aqueous ethanol, and water as solvents. The extract with the highest bioactive activity was encapsulated using corn and cassava starches as cell wall materials. The antioxidant activity, storage stability, in vitro starch digestibility and Fourier-transform infrared spectroscopy (FTIR) of the microcapsules were evaluated.
Results
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Authors: Chavhan, Sarin A.; Advisor: -; Participants: Bakal, Ravindra L.; Jawarkar, Rahul D.; Gandhi, Roshani P.; Chandak, Mayuri P.; Lewaa, Israa (2022) - Ionizing radiations causes harm to living organisms and the rapid technological progress has increased human exposure to ionizing radiations enormously. Ionizing radiations come in contact with exposure from space radiations, nuclear war, and radiotherapy for cancer-like disease.
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