- BB
Authors: Bhuiyan, Asma Akter; Advisor: -; Participants: Brahmachari, Sreyashi; Ripa, Israt Jahan; Noor, Rashed (2022) - At the end of December 2019, numerous people with pneumonia symptoms were admitted to the hospitals of Wuhan, Hubei region of China, and within a short period of time, it spread globally and became a pandemic (Liu et al. 2020). First, “Wuhan pneumonia” was coined to indicate the symptoms; soon after, it was discovered that the causative agent of the disease was “Coronavirus” which belongs to the “Coronaviridae” family and β coronavirus genus (Pal et al. 2020; Noor 2021; Noor and Maniha 2020). Subsequently, the name severe acute respiratory coronavirus 2 (SARS-CoV-2) took place (Pal et al. 2020). The World Health Organization (WHO) entitled this pandemic as “COVID-19” disease on March 11 2020, which consists of a genome sequence with an elevated degree of similarity with the earliest...
|
- BB
Authors: Borodo, Safiya Bala; Advisor: -; Participants: Jatau, Abubakar Ibrahim; Mohammed, Mustapha; Aminu, Nafiu; Shitu, Zayyanu; Sha’aban, Abubakar (2022) - The burden of polypharmacy and PIMs in Nigeria
In Nigeria, polypharmacy is common in clinical practice settings. Patients using between six and twelve medications have a higher risk of adverse drug events than patients with a lower quartile of drug use (Steinman et al. 2006). Akande and Ologe found that polypharmacy (particularly involving injectable formulations) and under-usage of life-saving drugs were common at a secondary healthcare facility in the North-central region of the country (Akande and Ologe 2007). The major risk factors for polypharmacy were reported as age, level of education, and diagnosis (Igbinomwanhia et al. 2017). The burden of polypharmacy had several clinical effects on the patients, ranging from medication non-compliance, addiction to drug interactions
|
- BB
Authors: Pawal, Pratibha; Advisor: -; Participants: Aute, Tukaram (2023) - Primary hypertriglyceridemia (HTG) is a very rare autosomal recessive disorder caused by the mutations of the genes related with triglyceride metabolism, including apolipoproteins and lipoprotein lipase (LPL) among others. Germline mutations in the LPL gene cause familial LPL deficiency with an incidence of about 1:1,000,000. It is often diagnosed in childhood and consanguinity is common.
|
- BB
Authors: Uttu, Ahmed Jibrin; Advisor: -; Participants: Sallau, Muhammad Sani; Iyun, Ogunkemi Risikat Agbeke; Ibrahim, Hamisu (2022) - Compounds isolated from plants have enormous potential in the development of new drugs (Sasidharan et al. 2011). In general, plants can be found all over the world, and their parts (leaves, stems, roots, fruit, and flowers) are employed in a variety of uses, including medicine (Umaru et al. 2019).
The phytochemical composition and secondary metabolites of plants such as coumarin and fatty alcohols contain active therapeutic components and are associated with their pharmacological potential (Mondal et al. 2019; Uttu et al. 2022). Umbelliferone (7-hydroxycoumarin) is sometimes utilized as a fluorophore. It has a large π–π conjugated system that allows it to be used as a fluorescent sensor for a variety of biological applications (Raunio et al. 2020), such as antidiarrheal, antiulce...
|
- BB
Authors: Mwangonela, Zena E.; Advisor: -; Participants: Ye, Young; Rachel, Qin; Msuya, Hajirani M.; Mwamlima, Tunu G.; Mswata, Sarah S.; Chaki, Prosper P.; Kimaro, Ester G.; . Mweya, Clement N; Mpina, Maxmillian G.; Mwangoka, Grace W. (2023) - Malaria rapid diagnostic tests (mRDTs) have played an important role in the early detection of clinical malaria in an endemic area. While several mRDTs are currently on the market, the availability of mRDTs with high sensitivity and specificity will merit the fight against malaria. We evaluated the field performance of a novel One Step Malaria (P.f/P.v) Tri-line and One Step Malaria (P.f) rapid test kits in Pwani, Tanzania.
|
 - BB
Authors: Uche-Okoye, Demelum; Advisor: -; Participants: Ajemba, Michael Nnaemeka; Amy, Bendall; Arene, Ebube Chinwe; Ugo, Chinemerem Henry; Eze, Ngozi Perpetua; Anyadike, Ikenna Kelechi; Onuorah, Uju Maryanne; Chiwenite, Chijioke Michael (2023) - Pulmonary rehabilitation (PR) has proven to improve the physical and psychosocial function in patients with chronic obstructive pulmonary disease (COPD). However, the gains achieved during pulmonary rehabilitation diminish over time without an effective maintenance strategy. With several factors affecting access to pulmonary rehabilitation, calls for innovative models were made, which saw the emergence of studies exploring telerehabilitation (TR) as an alternative to traditional pulmonary rehabilitation models. Although there are current reviews exploring the effectiveness of telerehabilitation as an alternative for conventional PR, no review has considered telerehabilitation effectiveness in the long term. Hence, this review aims at examining the effectiveness of telerehabilitation...
|
- BB
Authors: Osman, Hamida Ahmed; Advisor: -; Participants: Ameen, Hoda Hussein; Mohamed, Moawad; Elkelany, Usama Samy (2020) - Compared to the untreated control, all treatments exhibited variable potential inhibitory activities against root-knot nematode M. javanica and enhanced peanut yield production. The most nematode suppressive treatment was the single treatment of Saccharomyces cerevisiae, followed by T. harzianum either singly or combined with the yeast. Moreover, data indicated that application of the combined treatment of yeast plus T. harzianum gave the best results in improving peanut production, plant growth parameters, and seed nutrient contents.
|
- BB
Authors: Adeniji, Shola Elijah; Advisor: -; Participants: Arthur, David Ebuka; Abdullahi, Mustapha; Adalumo, Olajumoke Bosede (2020) - The established model was swayed with topological descriptors: MATS7s, SM1_DzZ, TDB3v, and RDF70v. More also, interactions between the compounds and the target “DNA gyrase” were evaluated via docking approach utilizing the PyRx and Discovery Studio simulated software. Meanwhile, compound 19 has the most perceptible binding affinity of − 16.5 kcal/mol. Consequently, compound 19 served as a reference structural template and insight to design twelve novel hypothetical agents with more competent activities. Meanwhile, compound 19h was observed with high activity among the designed compounds with more prominent binding affinities of − 21.6 kcal/mol.
|
- BB
Authors: Chikezie, Paul C.; Advisor: -; Participants: Ekeanyanwu, Raphael C.; Chile-Agada, Adaeze B. (2020) - The level of poly-dHbS-M of the control sample was significantly higher (p < 0.05) than those of the samples containing 40, 60, and 80 mg/100 mL ethylacetate extracts of A. occidentale at t < 60 s. The relative cumulative polymerization index (RCPI%) of dHbS-M in the presence of fractionated leaf extract of A. occidentale varied within a wide range of 3.8–59.4%. A. occidentale (petroleum ether and ethylacetate extracts), P. guajava (n-hexane, chloroform, and ethylacetate extracts), and T. catappa (ethylacetate extract) exhibited comparatively high potency to inhibit poly-dHbS-M.
|
- BB
Authors: El-Araby, R.; Advisor: -; Participants: Rezk, A. I.; El-Enin, S. A. Abo; Nofa, O. A.; El-Nasharty, A. B. (2020) - The ethanol has higher extraction efficiency and the ultrasonic probe recovered higher oil % in the blank sample. Seventeen samples of S. bigelovii cultivated under different combined treatments of fertilization and irrigation recorded oil % less than the blank sample. The fatty acids profile cleared that the oil of cultivated samples (17 samples) had power for biodiesel production with high ignition properties and good stability due to the high cetane number and a high percentage of palmitic acid. The nutrition value of the blank sample is higher than that of the other 17 samples. The polyunsaturated fatty acids in the blank sample represent > 63% of the total fatty acids.
|
