Item Infomation
Title: | Hospital discharges in urban sanitation systems: Long-term monitoring of wastewater resistome and microbiota in relationship to their eco-exposome |
Authors: | Buelow, E. |
Participants: | Rico, A. Gaschet, M. Lourenço, J. Kennedy, S.P. Wiest, L. Ploy, M-C. Dagot, C. |
Issue Date: | 2020 |
Series/Report no.: | Water Research X, Volume 7, 1 May 2020, 100045 |
Abstract: | Wastewaters (WW) are important sources for the dissemination of antimicrobial resistance (AMR) into the environment. Hospital WW (HWW) contain higher loads of micro-pollutants and AMR markers than urban WW (UWW). Little is known about the long-term dynamics of H and U WW and the impact of their joined treatment on the general burden of AMR. Here, we characterized the resistome, microbiota and eco-exposome signature of 126 H and U WW samples treated separately for three years, and then mixed, over one year. Multi-variate analysis and machine learning revealed a robust signature for each WW with no significant variation over time before mixing, and once mixed, both WW closely resembled Urban signatures. We demonstrated a significant impact of pharmaceuticals and surfactants on the resistome and microbiota of H and U WW. Our results present considerable targets for AMR related risk assessment of WW. |
URI: | http://tailieuso.tlu.edu.vn/handle/DHTL/10450 |
Source: | https://www.sciencedirect.com/science/article/pii/S2589914720300050 |
ISSN: | 2589-9147 |
Appears in Collections: | Tài liệu mở |
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