Antimicrobial and antioxidant activities of different extracts from Aspergillus unguis SPMD-EGY grown on different media

Abstract

Aspergillus unguis SPMD-EGY was isolated from the soft coral Sinularia sp. and was cultivated on different media. Three broth media potato dextrose broth (PDB), peptone yeast extract malt extract glucose (PYMG), and Dox media in addition to one solid medium (rice medium) were used for this purpose. The fungus was grown under shake and static conditions (for broth media only). Ethyl acetate extract from both mycelia and culture supernatant and the extract from the direct extraction of rice solid medium were tested for their antimicrobial and antioxidant activities. It has been found that PYMG medium (mycelia static and culture static) exhibited the highest antimicrobial activity against all test microbes except Aspergillus niger followed by PDB medium (culture static and mycelia static). From the antioxidant point of view, the PDB medium showed the highest antioxidant activity (culture-shake) followed by Dox medium (culture static and mycelia static). The obtained results have been assessed and compared to the results of previous works constructed. GC/MS analysis of the fungal extracts showing high significant antimicrobial activities was evaluated.