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Title: | Potent bioactive methanolic extract of wild orange (Citrus macroptera Mont.) shows antioxidative, anti-inflammatory, and antimicrobial properties in in vitro, in vivo, and in silico studies |
Authors: | Lala, Mousikha |
Participants: | Modak, Debabrata Paul, Subhashis Sarkar, Indrani Dutta, Ankita Kumar, Anoop Bhattacharjee, Soumen Sen, Arnab |
Issue Date: | 2020 |
Series/Report no.: | Bulletin of the National Research Centre, Volume 44 (2020), Article number: 81 |
Abstract: | At 200 μg/ml concentration, CML significantly scavenges reactive oxygen species (ROS) which was generated on HepG2 cell line. CML showed 71% anti-inflammatory activity (p ≤ 0.001) against carrageenan-induced paw edema in albino Wistar rats. CML extract is very effective against staphylococcus sp. than Klebsiella sp. In the docking analysis, the proximadiol and menthone had − 5.6 kcal/mol and − 5.7 kcal/mol binding affinity with the protein NF-ҡB. |
URI: | http://tailieuso.tlu.edu.vn/handle/DHTL/11370 |
Source: | https://bnrc.springeropen.com/articles/10.1186/s42269-020-00329-5 |
ISSN: | 2522-8307 |
Appears in Collections: | Tài liệu mở |
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