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Title: | In vitro assessment of deworming potential of Guiera senegalensis in Nigerian ethnoveterinary industry using Caenorhabditis elegans |
Authors: | Gagman, Haladu Ali |
Participants: | Ahmad, Hamdan Him, Nik Ahmad Irwan Izzaudin Nik Avicor, Silas Wintuma |
Issue Date: | 2022 |
Series/Report no.: | Bulletin of the National Research Centre, Volume 46 (2022), Article number: 3 |
Abstract: | Aqueous and methanol extracts of G. senegalensis were tested against the motility of the L4 larvae at two exposure periods of 24 and 48 h and found to be active against the C. elegans strains. Motility of C. elegans DA1316 was reduced to 18.6% and 8.3% by aqueous and methanol extracts, respectively, at 2.0 mg/ml after 48 h, whereas that of C. elegans DA1316 treated with ivermectin (0.02 µg/ml) remained above 95%. The motility of C. elegans Bristol N2 was reduced to 16.6% and 7.2% by aqueous and methanol extracts, respectively, at 2.0 mg/ml after 48 h and ≤ 2.7% by ivermectin (0.02 µg/ml). Activity of the plant extracts was concentration and time dependent. |
URI: | http://tailieuso.tlu.edu.vn/handle/DHTL/12601 |
Source: | https://link.springer.com/article/10.1186/s42269-021-00689-6 |
ISSN: | 2522-8307 |
Appears in Collections: | Tài liệu mở |
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