Item Infomation
Title: | Palm oil extracts protected against cadmium chloride poisoning via inhibition of oxidative stress in rats |
Authors: | Ichipi-Ifukor, Patrick Chukwuyenum |
Participants: | Asagba, Samuel Ogheneovo Mordi, Joseph Chukwufumnanya Nwose, Chibueze Oyem, John Chukwuma |
Issue Date: | 2022 |
Series/Report no.: | Bulletin of the National Research Centre, Volume 46 (2021), Article number: 5 |
Abstract: | Oxidative stress and antioxidant status (malondialdehyde, superoxide dismutase, catalase and glutathione) were assessed in tissues (liver, kidney, heart, brain, muscle) and serum. Oxidative stress indicators showed a significantly (p < 0.05) increased lipid peroxidation and alterations in antioxidant defence systems occasioned by drop in catalase and superoxide dismutase enzymes (serum, liver, heart, brain and kidneys) of the rats. Also observed were significant (p < 0.05) reduction in the non-enzymatic antioxidant reduced glutathione over time. Pre-administration of rats with the crude palm oil and its extracts modulated cadmium mediated depletion of the antioxidant capacities of rats acutely exposed to cadmium and rising lipid peroxidation profile. |
URI: | http://tailieuso.tlu.edu.vn/handle/DHTL/12604 |
Source: | https://link.springer.com/article/10.1186/s42269-021-00688-7 |
ISSN: | 2522-8307 |
Appears in Collections: | Tài liệu mở |
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