Origanum majorana L. extract alleviates dexamethasone-induced hepatotoxicity, oxidative stress and pathological alterations in vivo

Abstract

O. majorana alleviate Serum Liver Function Related Parameters in DXM treated rats Table 1 illustrates liver damage which obviously appeared as a significant elevated activities (P < 0.0001) of circulating enzymes in serum (ALT, AST, ALP and LDH) after DXM treatment. Conversely, O. majorana pretreated animals successfully improved liver function markers which restored and/ or reduced these enzyme activities to normal level