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Results 1-6 of 6 (Search time: 0.198 seconds).
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  • Early-pandemic wastewater surveillance of SARS-CoV-2 in Southern Nevada: Methodology, occurrence, and incidence/prevalence considerations

    • Authors: Gerrity, D.;  Advisor: -;  Participants: Papp, K.; Stoker, M.; Sims, A.; Frehner, W. (2021)

  • The current study aimed to compare the performance of virus recovery and detection methods, detect and quantify SARS-CoV-2 genetic material in two Southern Nevada sewersheds from March–May 2020, and better understand the potential link between COVID-19 incidence/prevalence and wastewater concentrations of SARS-CoV-2 RNA. SARS-CoV-2 surrogate recovery (0.34%–55%) and equivalent sample volume (0.1 mL–1 L) differed between methods and target water matrices, ultimately impacting method sensitivity and reported concentrations. Composite sampling of influent and primary effluent resulted in a ∼10-fold increase in concentration relative to corresponding grab primary effluent samples, presumably highlighting diurnal variability in SARS-CoV-2 signal. Detection and quantification of four SARS...
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  • The neuropathological impact of COVID-19: a review

    • Authors: Fouad, Ghadha Ibrahim;  Advisor: -;  Participants: - (2021)

  • The neuroinvasive potential of SARS-CoV-2 might contribute to its fatal behavior. Understanding the underlying mechanisms of this novel neuropathogen might contribute to the development of effective therapeutic strategies. The manifestations of neural damage in COVID-19 patients ranged from headache to severe encephalopathy and progression of preexisting neural disorders, it is speculated that neuroinvasion is strongly linked to the fatal respiratory dysfunction. The underlying neuropathological impact of emerging pneumonia (COVID-19) is still unclear.
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  • Phylogenetic and full-length genome mutation analysis of SARS-CoV-2 in Indonesia prior to COVID-19 vaccination program in 2021

    • Authors: Nidom, Reviany V.;  Advisor: -;  Participants: Indrasari, Setyarina; Normalina, Irine; Nidom, Astria N.; Afifah, Balqis; Dewi, Lestari; Putra, Andra K.; Ansori, Arif N. M.; Kusala, Muhammad K. J.; Alamudi, Mohammad Y.; Nidom, Chairul A. (2021)

  • All data of the isolates were extracted from the Global Initiative on Sharing All Influenza Data (GISAID) EpiCoV database. CoVsurver platform was employed to investigate the full-length genome mutation analysis of all isolates. This study also focused on the phylogeny analysis in unlocking the mutation of S protein in Indonesian SARS-CoV-2 isolates. WIV04 isolate that was originated from Wuhan, China was used as the virus reference according to the CoVsurver default. The result showed that a full-length genome mutation analysis of 166 Indonesian SARS-CoV-2 isolates was successfully generated. Every single mutation in S protein was described and then visualized by utilizing BioRender platform. Furthermore, it also found that D614G mutation appeared in 103 Indonesian SARS-CoV-2 isolat...
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  • An outline of SARS-CoV-2 pathogenesis and the complement cascade of immune system

    • Authors: Hembram, Padmalochan;  Advisor: -;  Participants: - (2021)

  • Coronavirus disease 19 is a viral infection caused by a novel coronavirus, SARS-CoV-2. It was first notified in Wuhan, China, is now spread into numerous part of the world. Thus, the world needs urgent support and encouragement to develop a vaccine or antiviral treatments to combat the atrocious outbreak.
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  • Recent updates on the possible reasons for the low incidence and morbidity of COVID-19 cases in Africa

    • Authors: Tsinda, Emmanuel Kagning;  Advisor: -;  Participants: Mmbando, Gideon Sadikiel (2021)

  • The COVID-19 respiratory illness caused by the SARS-CoV-2 has been a major cause of morbidity and mortality worldwide since the first reported case in Wuhan, China. A year has passed since pandemic began, and the reasons for different COVID-19 burden variation across continents keep puzzling the general public.
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