Item Infomation


Title: In vitro antimicrobial activity of lignan from the stem bark of Strombosia grandifolia Hook.f. ex Benth
Authors: Ekalu, A.
Participants: Ayo, Rachael Gbekele-Oluwa
Habila, J.D.
Hamisu, I.
Issue Date: 2019
Series/Report no.: Bulletin of the National Research Centre, Vol 43:115 (2019)
Abstract: The compound was active against tested microorganisms which included Staphylococcus aureus, Streptococcus pneumoniae, Escherichia coli, Salmonella typhi and Candida albicans using ciprofloxacin and terbinafine as standards. The zones of inhibition (ZOI) ranged between 11 and 17 mm for the compound against the microorganisms. The compound had a minimum inhibitory concentration (MIC) ranging from 0.75 to 3.0 mg/ml, and minimum bactericidal concentration (MBC) of 1.5, and a minimum fungicidal concentration (MFC) of 3.0 mg/ml. The lignan also showed antifungal activity against C. albicans. This experiment confirmed the efficacy of the lignan as a natural antimicrobial and suggested the possibility of employing it in drugs for the treatment of infectious diseases caused by the test organisms. This is the first report of the isolation of this compound from Strombosia grandifolia.
URI: http://tailieuso.tlu.edu.vn/handle/DHTL/10766
Source: https://bnrc.springeropen.com/articles/10.1186/s42269-019-0159-x
ISSN: 2522-8307
Appears in Collections:Tài liệu mở
ABSTRACTS VIEWS

39

VIEWS & DOWNLOAD

0

Files in This Item:
There are no files associated with this item.

Bạn đọc là cán bộ, giáo viên, sinh viên của Trường Đại học Thuỷ Lợi cần đăng nhập để Xem trực tuyến/Tải về



Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.